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RESEARCH ACTIVITIES & PROJECTS AT

COMMUNITY WELFARE SOCIETY HOSPITAL, ROURKELA

BACKGROUND & OBJECTIVES

               The Community Welfare Society Hospital (CWSH) is well recognized in the western Odisha as ‘a hospital with a difference’. This noble distinction of CWSH Rourkela is earned over the past decades by providing high-quality patient care to the sick and suffering. At the same time CWSH has set the grand vision that envisagesto develop this community dedicated hospital into a premiere healthcare institution with excellence in biomedical research.The research activities of CWS Hospital Rourkela are mandated to focus on the regional health concerns in the community and to address the underlying scientific challenges through specifically developed and designed research projects. The ultimate goal of which, is to provide the direct benefits to the local community, alongside to develop a state-of-the art research infrastructure in the hospital and highly trained research capacity.

July 2019, CWSH, Rourkela, Odisha

CSCMi ST3 -VBD WORKSHOP

ETHICS

               To maintain the highest standard of the research undertakings, to evaluate and regulate the policies of underlying human ethics, CWS Hospital constituted its own Institutional Ethical Committee (IEC) in 2018. It is a matter of great honor that this IEC at CWSH got officially registered under the Central Drugs Standard Control Organization (CDSCO) under Directorate General of Health Services (DGHS), Ministry of Health & Family Welfare (MoH&FW), Government of India (Regd. No- ECR/1306/Inst/OD/2019). Besides, CWS hospital has its own Scientific Advisory Committee (SAC) in place, for routine monitoring and regulation of research and development.

September 2019, Guwahati, Assam

CSCMi STAKEHOLDERS MEETING

AREAS OF RESEARCH

                The current research activities and projects that are ongoing at CWSH in several areas of research, include the following but is not limited to: life-threatening infectious diseases in humans e.g. Malaria, Scrub Typhus, and investigations of the Gut Microbiome at the molecular level. Besides these, there are upcoming research projects conceptualized by the Doctors and scientists at CWSH, for example-efficacy of new antimalarial drugs, molecular genetics of hemoglobinopathies, clinical spectrum and molecular characterization in diabetes, chronic kidney diseases etc., which are prevalent in the local regions.

Nov-Dec 2019, Kochi, Kerela.

FELICITATION OF DR. P K SAHU AND DR. M M PRADHAN & DR. A DAS ISMOCD CONFERENCE

RESEARCH COLLABORATION

               It is widely admissible that to keep up to the pace of frontier areas of clinical and biomedical research and innovation in today’s date, the need of collaboration has become almost prerequisite. Multi-institutional and multidisciplinary research initiatives are increasingly and evidently making their marks in developing innovative and path-breaking strategies with tangible research outcomes for even most complex and challenging objectives of clinical research. Through its consistent proactive participatory efforts over the past several years, the CWS Hospital at Rourkela has developed profound collaborative platforms for undertaking scientific research in the hospital. The present collaborative institutions are New York University (NYU) and National Institutes of Health (NIH), Govt of USA; National Institute of Technology (NIT), Rourkela and Health and Family Welfare (H&FW) Department, Govt. of Odisha. Future collaborations that are underway with CWS Hospital Rourkela are: University of Oxford, UK and Sambalpur University, Odisha.

Community Welfare Society Hospital (CWSH), Rourkela.

MOLECULAR BIOLOGY LAB CSCMi

ONGOING PROJECTS

1.  A cluster randomized trial to assess the effectiveness of malaria camps as part of the Odisha state malaria elimination drive (Phase 1,  CSCMi Study Type 3).

Project Leads: Dr Praveen K.Sahu, Sr Scientist & Dr. Sanjib Mohanty, Sr Consultant; Dept of Mol. Biology and Infectious Diseases, CWS Hospital, Rourkela.

Co-PI: Dr. Madan M Pradhan, ADPHO & State NVBDCP, H&FW Dept, Govt of Odisha.

Prog. Director: Dr. Jane Carlton, Professor, Dept of Biology, New York University, USA.​​

2.  A study on the emergence of Scrub typhus in patients with acute febrile illness.

Project Lead: Dr. Sanjib Mohanty MD, Senior Consultant, Dept of Molecular Biology and Infectious Diseases, CWS Hospital, Rourkela.

3.  Investigation on the comparison of gut microbiome of healthy and malnourished children in Sundargarh district of Odisha.

Project Lead: Dr. Karthika Parvathy, DST WOS-B Scientist, Food Microbiology & Bioprocess Lab, Dept of Life Sci., NIT Rourkela.

CSCMi-CWSH ST3 Team

EPIDEMIOLOGICAL SURVEYS 2019-2020

SUMMARY OF THE RESEARCH ACTIVITIES (Malaria project under CSCMi-CWSH)

               Malaria is a global public health concern, affecting millions of people. In many tropical and subtropical parts of the world just like Odisha, this mosquito-borne parasitic infection has high burden of morbidity and mortality in humans. Despite research advancement on antimalarials, vaccines, pathogenesis, and vector control, there lies numerous challenges ahead of Malaria elimination from the affected regions. Accordingly, there is a growing need for enhanced and focused malaria research efforts to fight the long-standing battle with malaria and ultimately help eliminate it from the globe. With this background and mandate, a Malaria Research Center was established in CWS Hospital Rourkela (CWSH) in 2018-19, by the Center for the Study of Complex Malaria in India (CSCMi) and New York University (NYU), USA under the International Centers of Excellence for Malaria Research (ICEMR-India) program of US-NIH. The current research aims to investigate the effectiveness of the Govt of Odisha’s malaria elimination drive Daman (Durgama Anchalare Malaria Nirakaran), which is undertaken in partnership with the Govt. of Odisha, Health and Family Welfare Department and New York University, USA, led by globally renowned malaria researcher and Genome Biologist Prof. Jane Carlton along with an interdisciplinary team of senior Faculties and Scientists from NYU, USA.

               A new Molecular Biology Laboratory was set-up at CWS Hospital equipped with modern scientific infrastructure for undertaking malaria research. Highly skilled and trained capacity for Lab and Field teams were engaged at CWSH, led by Dr. Praveen K Sahu (Molecular Biologist) and renowned Malaria Clinician-Researcher Dr. Sanjib Mohanty, with management support from Dr. MA Haque (Vector Coordinator) and Mr. TimirKPadhan (Project Coordinator). Alongside its primary research activities in the malaria affected districts in Odisha, the lab provides free-of-cost Malaria diagnosis to the patients of CWS Hospital Rourkela.

From Left to Right: Panigrahi S, Lakra J P, Ekka P, Toppo S R, Samal A G, Pradhan T K, Dr. Mohanty S, Dr. Sahu P K, Dr. Haque MA, Ekka S, Bage A, Dash S, Mohanty S, Chhatria S R.

CSCMi - ST3 TEAM AFTER YEAR-1 COMPLETION AT CWS HOSPITAL ROURKELA

HIGHLIGHTS OF THE RESEARCH UNDERTAKINGS AT CWSH

  • Successful research collaboration with international and national agencies e.g. NYU & NIH, USA; H & FW Govt. of Odisha; NIT Rourkela for major research projects.

  • Establishment of a state-of-the art Molecular Biology Laboratory in CWSH Rourkela.

  • Providing Free-of-cost diagnosis of malaria patients (OPD/IPD at CWSH Rourkela).

  • Successful epidemiological and entomological surveys of malaria elimination program (DAMaN) in malaria endemic districts in Odisha under CSCMi-ST3 project.

  • Hosting and organization of research workshops and training modules.

  • Publications and presentations of research data in scientific journals and national/international seminars, symposia.

MEDIA COVERAGE

  • NYU Global health News.

  • The New Indian Express.

  • Reporters Today.​

  • The Samaja.

  • The Sambad.​

  • The Pragativadi.

  • The Prameya.

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